Correcting BLAST e-Values for Low-Complexity Segments

نویسندگان
چکیده

منابع مشابه

Correcting BLAST e-Values for Low-Complexity Segments

The statistical estimates of BLAST and PSI-BLAST are of extreme importance to determine the biological relevance of sequence matches. While being very effective in evaluating most matches, these estimates usually overestimate the significance of matches in the presence of low complexity segments. In this paper, we present a model, based on divergence measures and statistics of the alignment str...

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ژورنال

عنوان ژورنال: Journal of Computational Biology

سال: 2005

ISSN: 1066-5277,1557-8666

DOI: 10.1089/cmb.2005.12.980